It will form part of the royal couple's annual Wales Week, in which they tour the country to publicise its positive aspects.
Their diary shows that on Wednesday 3rd July they will be meeting cast and crew members of Doctor Who during a set visit to the Roath Lock studios.
A spokesman for Clarence House, which is their official residence in London, said:
The Prince and the Duchess always enjoy their annual visit to Wales and this year they are looking forward to a varied programme of engagements including everything from Dylan Thomas's Boat House to Doctor Who's TARDIS! Their Royal Highnesses are also keen to highlight the vital work being done across Wales by some of the charities they are involved with.While they are at Roath Lock the couple will meet Matt Smith and Jenna-Louise Coleman, and will encounter some of the Doctor's enemies as well. It is not known as yet which production team members will be presented to Charles and Camilla.
This won't be the first official brush with the world of Doctor Who for the Duchess of Cornwall. While opening the West Wilts Show in Trowbridge in July 2009 she encountered a Dalek and TARDIS at a display dedicated to the programme.
Earlier this month, Coleman was presented to the Queen when the monarch officially opened the rebuilt Broadcasting House in London.